How sleep disruption and stress during adolescence affects alcohol addiction risk
Effects of circadian desynchrony during adolescent alcohol exposure on immediate and long-term risk of alcohol addiction: role of sleep homeostasis and stress signaling
['FUNDING_R01'] · UNIVERSITY OF SOUTH FLORIDA · NIH-11087583
This study is looking at how lack of sleep and stress can affect drinking habits in teens aged 12 to 20, and it hopes to find out if melatonin can help improve their sleep and reduce the risks of alcohol problems during this important time in their lives.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF SOUTH FLORIDA (nih funded) |
| Locations | 1 site (TAMPA, UNITED STATES) |
| Trial ID | NIH-11087583 on ClinicalTrials.gov |
What this research studies
This research investigates the impact of sleep disruption and stress on alcohol consumption among adolescents aged 12 to 20. By modeling circadian sleep patterns in adolescent mice, the study aims to understand how these factors contribute to the cycle of alcohol abuse and dependence. The researchers will explore the potential of melatonin to reset sleep patterns and mitigate the risks associated with alcohol use during this critical developmental period. The findings could lead to targeted interventions that address the unique needs of adolescents struggling with alcohol issues.
Who could benefit from this research
Good fit: Ideal candidates for this research are adolescents aged 12 to 20 who experience sleep disturbances and are at risk for alcohol abuse.
Not a fit: Patients outside the age range of 12 to 20 or those without sleep issues may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved strategies for preventing alcohol addiction in adolescents by addressing sleep and stress management.
How similar studies have performed: Previous research has shown that addressing sleep and stress can positively influence substance use behaviors, suggesting a promising avenue for this study.
Where this research is happening
TAMPA, UNITED STATES
- UNIVERSITY OF SOUTH FLORIDA — TAMPA, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: GULICK, DANIELLE — UNIVERSITY OF SOUTH FLORIDA
- Study coordinator: GULICK, DANIELLE
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: addictive disorder