How sleep disruption affects recovery of memory after brain injury.
Official title: Chronic sleep disruption as prognostic biomarker of cognitive recovery following traumatic brain injury.
Funded at Philadelphia VA Medical Center · NIH-11003753 · Data updated 2026-11-12
This study looks at how ongoing sleep problems affect memory and thinking skills in veterans and service members who have had a traumatic brain injury, with the goal of finding better ways to help them recover.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Philadelphia VA Medical Center NIH-funded |
| Lab location | 1 site (Philadelphia, United States) |
| Project start | January 1, 2024 |
| Project end | December 31, 2025 |
| Funding year | 2025 |
| NIH project number | 5I21RX004629-02 |
| Project ID | NIH-11003753 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals, particularly veterans and service members, who have experienced a traumatic brain injury and are suffering from chronic sleep disruptions.
✕Less likely to help
Patients who have not experienced a traumatic brain injury or do not have sleep disturbances may not benefit from this research.
What this research studies
This research investigates the impact of chronic sleep disruption on cognitive recovery in individuals who have suffered a traumatic brain injury (TBI). It explores how sleep disturbances can complicate memory formation and consolidation, which are critical for cognitive function. By examining the mechanisms behind these cognitive deficits, the study aims to improve the management of recovery in affected individuals, particularly focusing on veterans and service members. The research employs advanced techniques like in vivo electrophysiology to analyze sleep patterns and brain activity in relation to memory processing.
Why it matters
Potential benefit: If successful, this research could lead to improved strategies for enhancing cognitive recovery in patients with traumatic brain injuries.
How similar studies have gone: Previous research has indicated that addressing sleep disturbances can positively influence cognitive recovery in brain injury patients, suggesting a promising avenue for this investigation.
Where this research is happening
-
Philadelphia VA Medical Center
Philadelphia, United States Active
Researchers
- Principal investigator: Ulyanova, Alexandra V. — Philadelphia VA Medical Center
- Study coordinator: Ulyanova, Alexandra V.
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.