How sleep connects to diabetes, blood pressure, and memory in diverse Hispanic/Latino adults
Leveraging omics data to understand sleep health and its consequences among diverse Hispanics/Latinos
This project uses blood and DNA markers to find links between sleep problems and risks for diabetes, high blood pressure, and memory loss in Hispanic/Latino adults.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Beth Israel Deaconess Medical Center NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-11129850 on NIH RePORTER |
What this research studies
This work uses sleep measurements and stored biological samples from the long-running Hispanic Community Health Study/Study of Latinos (HCHS/SOL), which followed about 16,500 people from multiple Latino backgrounds. Researchers will look for metabolomics and DNA methylation patterns tied to different sleep traits and then study how those patterns relate to diabetes, hypertension, and cognitive decline. They will also connect molecular signals to lifestyle and sociocultural factors to find modifiable risks. The team aims to combine these signals into biomarkers that could help identify who is at higher risk because of poor sleep.
Who could benefit from this research
Good fit: Ideal candidates mirror the HCHS/SOL cohort: Hispanic/Latino adults, especially those with sleep problems or with diabetes, hypertension, or early memory concerns.
Not a fit: People without sleep issues, non-Hispanic/Latino individuals, or those from groups not represented in the cohort may not gain direct benefit from the findings.
Why it matters
Potential benefit: If successful, the project could produce blood-based markers that help detect people whose sleep increases their chance of diabetes, high blood pressure, or cognitive decline so prevention can start earlier.
How similar studies have performed: Prior studies have linked sleep problems to metabolic and cognitive outcomes and found small metabolomic or methylation signals, but applying multiple omics in a large, diverse Latino cohort is relatively new.
Where this research is happening
Boston, United States
- Beth Israel Deaconess Medical Center — Boston, United States (Active)
Researchers
- Principal investigator: Sofer, Tamar — Beth Israel Deaconess Medical Center
- Study coordinator: Sofer, Tamar
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.