NIH-funded research NIH-funded research

How sleep and inflammation affect chronic pain after shoulder surgery

Official title: Differential Susceptibility for Developing Chronic Post-Surgical Pain Across Sleep Trajectories and Inflammatory Presentations

Funded at Emory University · NIH-11010335 · Data updated 2026-11-12

This study is looking at how your sleep habits might affect your chances of having long-lasting pain after shoulder surgery, and it’s for anyone who’s had or is planning to have shoulder surgery.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionEmory University
NIH-funded
Lab location1 site (Atlanta, United States)
Project startFebruary 1, 2023
Project endJanuary 31, 2028
Funding year2025
Award (this year)$192,780
NIH project number5K23DA057415-03
Project IDNIH-11010335 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are individuals scheduled for shoulder surgery who experience sleep disturbances or have a history of chronic pain.

Less likely to help

Patients who do not have shoulder conditions or those without sleep issues may not benefit from this research.

What this research studies

This research investigates the relationship between sleep patterns and the development of chronic pain following shoulder surgery. It focuses on how insufficient sleep and increased inflammation may contribute to a higher risk of chronic post-surgical pain. By using wearable technology to monitor sleep and pain levels in real-time, the study aims to identify patients who are more susceptible to chronic pain based on their sleep quality and inflammatory responses. The findings could lead to better pain management strategies for patients undergoing shoulder arthroplasty.

Why it matters

Potential benefit: If successful, this research could help identify patients at risk for chronic pain and improve postoperative pain management strategies.

How similar studies have gone: Previous research has shown that sleep quality significantly impacts pain outcomes, suggesting that this approach could yield valuable insights.

Where this research is happening

  • Emory University
    Atlanta, United States
    Active

Researchers

  • Principal investigator: Giordano, Nicholas a — Emory University
  • Study coordinator: Giordano, Nicholas a

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
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Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.