How sleep and circadian timing affect heart and metabolic health in teens with type 1 diabetes
Official title: Mechanisms underlying the relationship between sleep health and circadian timing with cardiometabolic risk in adolescents with type 1 diabetes
Funded at University of Colorado Denver · NIH-10948592 · Data updated 2026-11-12
This study is looking at how better sleep and a regular daily schedule can help teenagers with type 1 diabetes stay healthier and lower their risk of heart and metabolic problems.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Colorado Denver NIH-funded |
| Lab location | 1 site (Aurora, UNITED STATES) |
| Project start | September 1, 2024 |
| Project end | August 31, 2029 |
| Funding year | 2024 |
| Award (this year) | $524,390 |
| NIH project number | 1R01HL174735-01 |
| Project ID | NIH-10948592 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are adolescents aged 12 to 20 years who have been diagnosed with type 1 diabetes.
✕Less likely to help
Patients who do not have type 1 diabetes or are outside the age range of 12 to 20 years may not benefit from this research.
What this research studies
This research investigates the connection between sleep health, circadian timing, and cardiometabolic risk in adolescents with type 1 diabetes. The study aims to understand how improving sleep and aligning circadian rhythms can potentially reduce health risks associated with diabetes. By employing a combination of behavioral and physiological interventions, the researchers hope to enhance sleep duration and advance circadian timing in these adolescents. The ultimate goal is to identify effective strategies to improve overall cardiometabolic health in this vulnerable population.
Why it matters
Potential benefit: If successful, this research could lead to improved heart and metabolic health outcomes for adolescents with type 1 diabetes.
How similar studies have gone: Previous research has shown success in improving sleep and circadian timing in adolescents without diabetes, but this specific approach in adolescents with type 1 diabetes is novel.
Where this research is happening
-
University of Colorado Denver
Aurora, United States Active
Researchers
- Principal investigator: Simon, Stacey Lynn — University of Colorado Denver
- Study coordinator: Simon, Stacey Lynn
Related research
Other NIH-funded projects on the same topics.
-
Technological and Educational Approaches to Restore Hypoglycemia Awareness in Type 1 Diabetes
A two-arm study in adults with type 1 diabetes tests whether high-tech glucose control plus education or targeted training can help people regain awareness of low blood sugar.
-
Techniques for restoring awareness of low blood sugar in adults with type 1 diabetes
A randomized trial compares different approaches to help adults with type 1 diabetes recognize when their blood sugar is dipping so they can act quickly.
-
Treating impaired hypoglycemia awareness in type 1 diabetes with targeted education and technology
This study tests two treatment approaches to help adults with type 1 diabetes who often don’t realize their blood sugar is getting too low, using a mix of technology and education in two large groups.
-
Helping people with type 1 diabetes regain awareness of dangerous lows
A UK study tests two different approaches to help adults with type 1 diabetes recognize and respond to low blood sugar by comparing a high-tech insulin system with targeted education.
-
How the pancreas environment affects insulin-producing cells in type 1 diabetes
Researchers are studying how the surrounding tissue of the pancreas and its proteins influence insulin-producing cells in people with type 1 diabetes.
-
Understanding how hypoglycemia awareness changes in adults with type 1 diabetes and how automated insulin delivery and exercise might help restore it
This study will look at adults with type 1 diabetes to see how their awareness of low blood sugar evolves over time and whether automated insulin delivery and high-intensity exercise can help restore that awareness.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.