NIH-funded research R01 grant

How sleep and circadian rhythms affect nighttime blood pressure

Official title: Sleep and Circadian Contributions to Nighttime Blood Pressure Rhythms (SCN-BP)

Funded at University of Alabama at Birmingham · NIH-11090545 · Data updated 2026-11-12

This study is looking at how your sleep habits and body clock affect your blood pressure at night, and it’s for anyone interested in finding ways to lower their nighttime blood pressure and improve heart health.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Alabama at Birmingham
NIH-funded
Lab location1 site (Birmingham, United States)
Project startJune 1, 2023
Project endMay 31, 2028
Funding year2025
Award (this year)$554,524
NIH project number5R01HL167230-03
Project IDNIH-11090545 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research include individuals experiencing high nighttime blood pressure or those at risk for cardiovascular diseases.

Less likely to help

Patients who do not have issues with blood pressure regulation or who are not at risk for cardiovascular diseases may not benefit from this research.

What this research studies

This research investigates the relationship between sleep patterns, circadian rhythms, and nighttime blood pressure levels. By collecting data through questionnaires and wrist actigraphy, the study aims to understand how factors like chronotype and sleep timing influence blood pressure dipping during sleep. The research involves a diverse group of participants across multiple sites, focusing on developing interventions to lower nighttime blood pressure and reduce cardiovascular disease risk. The findings could lead to personalized strategies for managing blood pressure based on individual sleep and circadian profiles.

Why it matters

Potential benefit: If successful, this research could lead to improved management of nighttime blood pressure, reducing the risk of cardiovascular diseases for patients.

How similar studies have gone: Previous research has shown promising results in understanding the impact of sleep and circadian rhythms on blood pressure, suggesting that this approach could yield significant insights.

Where this research is happening

  • University of Alabama at Birmingham
    Birmingham, United States
    Active

Researchers

  • Principal investigator: Thomas, Stephen J — University of Alabama at Birmingham
  • Study coordinator: Thomas, Stephen J

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.