How sleep affects the risk of developing Alzheimer's disease
Contributions of sleep to preclinical and clinical Alzheimer's disease
['FUNDING_R01'] · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · NIH-10581537
This study is looking at how different sleep habits might affect the chances of developing Alzheimer's disease, and it's for people who want to understand how improving their sleep could help protect their brain health.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF TEXAS HLTH SCIENCE CENTER (nih funded) |
| Locations | 1 site (SAN ANTONIO, UNITED STATES) |
| Trial ID | NIH-10581537 on ClinicalTrials.gov |
What this research studies
This research investigates the relationship between various aspects of sleep and the risk of developing Alzheimer's disease. By analyzing data from five large population-based cohorts, the study aims to identify specific sleep metrics that may contribute to the onset of dementia. Participants will undergo detailed overnight sleep studies, known as polysomnography, to gather comprehensive data on their sleep patterns. The findings could lead to targeted sleep interventions designed to reduce the risk of Alzheimer's disease.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals at risk for Alzheimer's disease, particularly those with sleep disturbances or cognitive decline.
Not a fit: Patients who are not at risk for Alzheimer's disease or do not experience sleep issues may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for preventing Alzheimer's disease through improved sleep health.
How similar studies have performed: Previous research has shown promising results in understanding the link between sleep and cognitive decline, suggesting that this approach may yield valuable insights.
Where this research is happening
SAN ANTONIO, UNITED STATES
- UNIVERSITY OF TEXAS HLTH SCIENCE CENTER — SAN ANTONIO, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: HIMALI, JAYANDRA JUNG — UNIVERSITY OF TEXAS HLTH SCIENCE CENTER
- Study coordinator: HIMALI, JAYANDRA JUNG
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Alzheimer disease dementia, Alzheimer syndrome, Alzheimer's Disease