How sleep affects memory and context in humans

The role of context in sleep-related memory reactivation in humans

['FUNDING_OTHER'] · UNIVERSITY OF CALIFORNIA-IRVINE · NIH-10989922

This study is looking at how the environment around us can help bring back memories while we sleep, which is important for making those memories stronger, and it could lead to new ways to help people with memory problems, especially those dealing with post-traumatic stress disorder.

Quick facts

Phase['FUNDING_OTHER']
Study typeNih_funding
SexAll
SponsorUNIVERSITY OF CALIFORNIA-IRVINE (nih funded)
Locations1 site (IRVINE, UNITED STATES)
Trial IDNIH-10989922 on ClinicalTrials.gov

What this research studies

This research investigates the role of context in the reactivation of memories during sleep, which is essential for memory consolidation. By exploring how memories are influenced by their surrounding context, the study aims to develop a framework that connects memory processes with sleep-related consolidation. The researchers will employ innovative techniques, including machine-learning algorithms, to manipulate memory reactivation during sleep. This could lead to new interventions for individuals with memory-related issues, particularly those suffering from conditions like post-traumatic stress disorder.

Who could benefit from this research

Good fit: Ideal candidates for this research include individuals experiencing memory-related issues, particularly those with post-traumatic stress disorder.

Not a fit: Patients without memory-related disorders or those not experiencing significant sleep disturbances may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to new therapeutic strategies for improving memory and alleviating symptoms in patients with memory-related disorders.

How similar studies have performed: Previous research has shown promising results in understanding the relationship between sleep and memory, suggesting that this approach could yield significant insights.

Where this research is happening

IRVINE, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.