How skin inflammation affects gut health
Inflammatory cross-talk between skin and gut
This study is looking at how skin problems might affect gut health, especially for people with inflammatory bowel diseases, and it will involve patients sharing samples or information to help researchers understand this connection better.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Diego NIH-funded |
| Lab location | 1 site (La Jolla, United States) |
| Project ID | NIH-10794363 on NIH RePORTER |
What this research studies
This research investigates the connection between skin inflammation and gut health, focusing on how skin injuries can influence intestinal conditions. The study will explore the role of hyaluronic acid released from the skin's extracellular matrix and its effects on gut inflammation and microbiome composition. By examining the communication between skin and gut tissues, researchers aim to understand how skin conditions can exacerbate inflammatory bowel diseases. Patients may be involved in providing samples or data to help elucidate these mechanisms.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals with inflammatory bowel diseases who also experience skin conditions.
Not a fit: Patients without any skin conditions or those not suffering from inflammatory bowel diseases may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments for patients suffering from inflammatory bowel diseases by targeting skin-related factors.
How similar studies have performed: Other research has indicated that interactions between different body systems can significantly impact health, suggesting that this approach may yield valuable insights.
Where this research is happening
La Jolla, United States
- University of California, San Diego — La Jolla, United States (Active)
Researchers
- Principal investigator: Gallo, Richard L — University of California, San Diego
- Study coordinator: Gallo, Richard L
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.