How skin heals after injury in living animals
Understanding Skin Tissue Repair in Live Mammals
This study looks at how different types of skin cells work together to heal wounds in live mice, helping us learn more about how skin repairs itself and could lead to better treatments for chronic wounds and skin cancer.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Yale University NIH-funded |
| Lab location | 1 site (New Haven, United States) |
| Project ID | NIH-10907775 on NIH RePORTER |
What this research studies
This research investigates the mechanisms of skin tissue repair in live mammals, focusing on how different cell types, such as epithelial cells and fibroblasts, work together to heal wounds. The study utilizes advanced techniques to visualize and manipulate these cells in real-time within the skin of live mice, allowing researchers to observe the dynamic processes involved in healing. By understanding how genetically diverse cells contribute to repair, the research aims to uncover new insights into chronic wound healing and skin cancer development.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with chronic wounds or conditions affecting skin healing.
Not a fit: Patients with acute injuries or those not experiencing skin healing issues may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments for chronic wounds and better understanding of skin cancer.
How similar studies have performed: Other research has shown success in understanding tissue repair mechanisms, but this approach of studying genetically diverse cells in live mammals is relatively novel.
Where this research is happening
New Haven, United States
- Yale University — New Haven, United States (Active)
Researchers
- Principal investigator: Greco, Valentina — Yale University
- Study coordinator: Greco, Valentina
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.