How skin cells communicate and grow during development and healing in zebrafish
Mechanism of epidermal coordination during development and regeneration in zebrafish
['FUNDING_CAREER'] · DUKE UNIVERSITY · NIH-11036268
This study looks at how skin cells in zebrafish work together to grow and heal, which could help us learn better ways to treat skin injuries in people.
Quick facts
| Phase | ['FUNDING_CAREER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | DUKE UNIVERSITY (nih funded) |
| Locations | 1 site (DURHAM, UNITED STATES) |
| Trial ID | NIH-11036268 on ClinicalTrials.gov |
What this research studies
This research investigates how skin cells in zebrafish coordinate their growth and behavior during both development and tissue regeneration. By using advanced imaging techniques, the study aims to understand the mechanisms that allow different layers of skin cells to communicate effectively, especially during rapid growth phases. The researchers will explore the effects of tissue tension and geometry on skin cell behavior, which could provide insights into how similar processes occur in humans. The findings may lead to improved strategies for healing damaged skin and other tissues in human patients.
Who could benefit from this research
Good fit: Ideal candidates for benefiting from this research include individuals with skin injuries or conditions that require regeneration or healing.
Not a fit: Patients with non-skin related conditions or those who do not require tissue regeneration may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better treatments for skin injuries and diseases in humans.
How similar studies have performed: Other research has shown success in understanding cell communication and regeneration in various models, making this approach promising.
Where this research is happening
DURHAM, UNITED STATES
- DUKE UNIVERSITY — DURHAM, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: RAMKUMAR, NITYA — DUKE UNIVERSITY
- Study coordinator: RAMKUMAR, NITYA
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.