How sex hormones affect Chlamydia infections
The Effects of Sex Hormones on Chlamydia Infection
['FUNDING_OTHER'] · UNIVERSITY OF MARYLAND BALTIMORE · NIH-11290896
This study is looking at how sex hormones and the bacteria in the vagina interact with Chlamydia infections, using a special model to better understand these relationships, which could help improve prevention and treatment for people dealing with Chlamydia.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF MARYLAND BALTIMORE (nih funded) |
| Locations | 1 site (BALTIMORE, UNITED STATES) |
| Trial ID | NIH-11290896 on ClinicalTrials.gov |
What this research studies
This research investigates the interactions between sex hormones, the cervicovaginal microbiota, and Chlamydia trachomatis infections. By developing a biomimetic model that mimics the cervicovaginal environment, the study aims to understand how these interactions influence the body's response to infection. The research employs advanced techniques such as global transcriptomics and immune profiling to gather comprehensive data on host and pathogen behavior. Patients may benefit from insights that could lead to improved prevention and treatment strategies for Chlamydia infections.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals who are sexually active and may be at risk for Chlamydia infections, particularly those with varying levels of sex hormone exposure.
Not a fit: Patients who are not sexually active or those who have no history of Chlamydia or related infections may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better understanding and management of Chlamydia infections, potentially improving treatment outcomes for affected patients.
How similar studies have performed: Previous research has shown promise in understanding host-pathogen interactions using biomimetic models, suggesting that this approach could yield valuable insights.
Where this research is happening
BALTIMORE, UNITED STATES
- UNIVERSITY OF MARYLAND BALTIMORE — BALTIMORE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: DERRE, ISABELLE — UNIVERSITY OF MARYLAND BALTIMORE
- Study coordinator: DERRE, ISABELLE
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.