How sex hormones affect brain development during puberty
Endocrine-mediated pubertal brain network development: Bridging datasets with machine learning
This study is looking at how hormones like estradiol and testosterone affect brain development during puberty, and it's for young people who want to understand how these changes might shape their brains as they grow up.
Quick facts
| Grant type | Career grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Southern California NIH-funded |
| Lab location | 1 site (Los Angeles, UNITED STATES) |
| Project ID | NIH-11004972 on NIH RePORTER |
What this research studies
This research investigates the impact of sex hormones on brain development during puberty by utilizing advanced neuroimaging techniques and machine learning. It aims to understand how hormones like estradiol and testosterone influence brain structure and function, particularly focusing on changes in brain architecture. By analyzing data from youth at different stages of puberty, the study seeks to uncover the relationship between hormone levels and brain development, addressing gaps in current knowledge. The approach combines insights from animal studies with innovative human neuroimaging methods to provide a comprehensive view of these biological processes.
Who could benefit from this research
Good fit: Ideal candidates for this research are adolescents aged 12 to 20 who are undergoing puberty and may be experiencing psychological or developmental challenges.
Not a fit: Patients outside the age range of 12 to 20 or those not undergoing puberty may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding of adolescent brain development and inform interventions for psychological conditions during this critical period.
How similar studies have performed: Previous research has shown promising results in understanding hormonal influences on brain development, but this specific approach integrating machine learning and neuroimaging is relatively novel.
Where this research is happening
Los Angeles, UNITED STATES
- University of Southern California — Los Angeles, United States (Active)
Researchers
- Principal investigator: Bottenhorn, Katherine Louise — University of Southern California
- Study coordinator: Bottenhorn, Katherine Louise
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.