How sex differences affect brain injury and recovery in children
The Effect of Sex Dimorphisms on TBI Injury and Recovery
['FUNDING_R21'] · UNIVERSITY OF GEORGIA · NIH-10861086
This study is looking at how boys and girls might recover differently from traumatic brain injuries in kids aged 0-14, using a pig model to help us understand these differences better, so we can create more effective treatments for both boys and girls.
Quick facts
| Phase | ['FUNDING_R21'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF GEORGIA (nih funded) |
| Locations | 1 site (ATHENS, UNITED STATES) |
| Trial ID | NIH-10861086 on ClinicalTrials.gov |
What this research studies
This research investigates how biological differences between boys and girls may influence the severity of traumatic brain injuries (TBI) and their recovery in children aged 0-14. By using a pediatric pig model, the study aims to understand how these differences in brain structure affect neural recovery and cognitive, behavioral, and motor functions after a TBI. The research will track changes over different recovery time points to identify specific patterns related to sex. This could lead to better treatment strategies tailored to the needs of male and female children.
Who could benefit from this research
Good fit: Ideal candidates for this research are children aged 0-14 who have experienced a traumatic brain injury.
Not a fit: Patients who are older than 14 years or have not experienced a traumatic brain injury may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatment and recovery strategies for children suffering from traumatic brain injuries based on their sex.
How similar studies have performed: Previous research has indicated that understanding sex differences in brain injuries can lead to significant advancements in treatment, suggesting this approach has potential for success.
Where this research is happening
ATHENS, UNITED STATES
- UNIVERSITY OF GEORGIA — ATHENS, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: WEST, FRANKLIN D — UNIVERSITY OF GEORGIA
- Study coordinator: WEST, FRANKLIN D
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.