How sex differences affect brain injury and recovery in children
Official title: The Effect of Sex Dimorphisms on TBI Injury and Recovery
Funded at University of Georgia · NIH-10861086 · Data updated 2026-11-12
This study is looking at how boys and girls might recover differently from traumatic brain injuries in kids aged 0-14, using a pig model to help us understand these differences better, so we can create more effective treatments for both boys and girls.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Georgia NIH-funded |
| Lab location | 1 site (Athens, United States) |
| Project start | June 15, 2023 |
| Project end | May 31, 2026 |
| Funding year | 2024 |
| Award (this year) | $213,000 |
| NIH project number | 5R21NS131526-02 |
| Project ID | NIH-10861086 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are children aged 0-14 who have experienced a traumatic brain injury.
✕Less likely to help
Patients who are older than 14 years or have not experienced a traumatic brain injury may not benefit from this research.
What this research studies
This research investigates how biological differences between boys and girls may influence the severity of traumatic brain injuries (TBI) and their recovery in children aged 0-14. By using a pediatric pig model, the study aims to understand how these differences in brain structure affect neural recovery and cognitive, behavioral, and motor functions after a TBI. The research will track changes over different recovery time points to identify specific patterns related to sex. This could lead to better treatment strategies tailored to the needs of male and female children.
Why it matters
Potential benefit: If successful, this research could lead to improved treatment and recovery strategies for children suffering from traumatic brain injuries based on their sex.
How similar studies have gone: Previous research has indicated that understanding sex differences in brain injuries can lead to significant advancements in treatment, suggesting this approach has potential for success.
Where this research is happening
-
University of Georgia
Athens, United States Active
Researchers
- Principal investigator: West, Franklin D — University of Georgia
- Study coordinator: West, Franklin D
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.