How sex affects breathing responses to wood smoke exposure
Impact of sex on respiratory response to wood smoke exposure
This study is looking at how men and women’s lungs react differently to wood smoke, which can affect breathing, to help us better understand respiratory health and the effects of air pollution.
Quick facts
| Grant type | Career grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Univ of North Carolina Chapel Hill NIH-funded |
| Lab location | 1 site (Chapel Hill, United States) |
| Project ID | NIH-10734060 on NIH RePORTER |
What this research studies
This research investigates how male and female bodies respond differently to wood smoke exposure, focusing on respiratory health. It aims to understand the physiological and immune responses in the lungs when exposed to air pollutants like wood smoke. The study will involve both in vivo assessments of lung function and ex vivo experiments with lung cells to explore the effects of sex hormones on these responses. By identifying these differences, the research seeks to enhance our understanding of respiratory health and the impact of air pollution.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals who have been exposed to wood smoke and have respiratory issues, particularly those who identify as male or female.
Not a fit: Patients with respiratory conditions unrelated to air pollution exposure may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved respiratory health strategies tailored to the specific needs of different sexes exposed to air pollutants.
How similar studies have performed: While research on air pollution and respiratory health is extensive, the specific focus on sex differences in response to wood smoke exposure is relatively novel and underexplored.
Where this research is happening
Chapel Hill, United States
- Univ of North Carolina Chapel Hill — Chapel Hill, United States (Active)
Researchers
- Principal investigator: Rebuli, Meghan Elizabeth — Univ of North Carolina Chapel Hill
- Study coordinator: Rebuli, Meghan Elizabeth
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.