How serotonin affects the body's stress response
Official title: Serotonergic control of the sympathoadrenal stress response
Funded at Rowan University · NIH-10654226 · Data updated 2026-11-12
This study is looking at how a gene related to serotonin might affect how our bodies handle stress, which could help us understand conditions like depression, anxiety, and autism better.
Quick facts
| Grant type | R15 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Rowan University NIH-funded |
| Lab location | 1 site (Glassboro, United States) |
| Project start | May 15, 2023 |
| Project end | April 30, 2026 |
| Funding year | 2023 |
| Award (this year) | $483,000 |
| NIH project number | 1R15NS132585-01 |
| Project ID | NIH-10654226 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals with depression, anxiety disorders, or autism spectrum disorder.
✕Less likely to help
Patients with stress-related conditions not linked to serotonergic signaling may not benefit from this research.
What this research studies
This research investigates the role of the serotonin transporter (SERT) in regulating the body's response to stress. It focuses on how genetic variations in SERT can influence conditions like depression, anxiety, and autism. By studying adrenal chromaffin cells, which are involved in the release of stress hormones, the research aims to uncover the mechanisms by which serotonin affects stress responses. This could lead to a better understanding of autonomic dysfunction and related health issues.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments for stress-related conditions and better management of symptoms in patients with depression, anxiety, and autism.
How similar studies have gone: Previous research has shown promising results in understanding the role of serotonin in stress responses, suggesting that this approach could yield valuable insights.
Where this research is happening
-
Rowan University
Glassboro, United States Active
Researchers
- Principal investigator: Currie, Kevin P — Rowan University
- Study coordinator: Currie, Kevin P
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.