How serine and glycine affect muscle healing in older adults
The essentiality of serine and glycine for skeletal muscle regeneration in aging
This study is looking at how two important nutrients, serine and glycine, can help older adults heal and rebuild their muscles after injury by supporting the growth of special cells that repair muscle damage.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Alabama at Birmingham NIH-funded |
| Lab location | 1 site (Birmingham, United States) |
| Project ID | NIH-10987045 on NIH RePORTER |
What this research studies
This research investigates the role of the amino acids serine and glycine in the regeneration of skeletal muscle, particularly in older adults. It aims to understand how these nutrients influence the activation and growth of muscle stem cells, which are crucial for repairing muscle damage. By using advanced techniques to trace the metabolism of these amino acids, the study will explore how their availability impacts muscle recovery after injury and the overall muscle environment in aging individuals.
Who could benefit from this research
Good fit: Ideal candidates for this research are older adults experiencing muscle loss or impaired muscle regeneration due to aging.
Not a fit: Patients who are younger and do not have issues with muscle regeneration or those with conditions unrelated to muscle health may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved dietary recommendations or treatments that enhance muscle regeneration in older adults, potentially improving their mobility and quality of life.
How similar studies have performed: Previous research has shown that dietary interventions can positively influence muscle health, suggesting that this approach may yield beneficial results.
Where this research is happening
Birmingham, United States
- University of Alabama at Birmingham — Birmingham, United States (Active)
Researchers
- Principal investigator: Thalacker-Mercer, Anna E. — University of Alabama at Birmingham
- Study coordinator: Thalacker-Mercer, Anna E.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.