How sensorimotor function relates to Alzheimer's disease and dementia risk
Contribution of sensorimotor function to risk and pathogenic mechanisms of Alzheimer's disease and related dementias
This study is looking at how changes in your senses and movement might be early signs of Alzheimer's disease and related conditions, and it's for older adults who want to understand their risk of developing memory problems.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Johns Hopkins University NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project ID | NIH-10534237 on NIH RePORTER |
What this research studies
This research investigates how changes in sensory and motor functions may serve as early indicators of Alzheimer's disease (AD) and related dementias. By analyzing data from around 1,000 older adults, the study aims to identify links between sensory impairments, gait abnormalities, and cognitive decline. It utilizes advanced imaging techniques and biomarkers to understand the relationship between these physical changes and the onset of dementia. The goal is to develop a predictive model that can help assess the risk of progression to mild cognitive impairment or Alzheimer's disease.
Who could benefit from this research
Good fit: Ideal candidates for this research are older adults, particularly those showing early signs of cognitive decline or sensory impairments.
Not a fit: Patients who are not elderly or do not exhibit any sensory or cognitive impairments may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to earlier detection and intervention strategies for Alzheimer's disease, potentially improving patient outcomes.
How similar studies have performed: Previous research has shown promising results in identifying early biomarkers for Alzheimer's disease, suggesting that this approach may yield valuable insights.
Where this research is happening
Baltimore, United States
- Johns Hopkins University — Baltimore, United States (Active)
Researchers
- Principal investigator: Schrack, Jennifer Ann — Johns Hopkins University
- Study coordinator: Schrack, Jennifer Ann
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.