How selenium affects heat production in cold temperatures
Selenium metabolism in cold-induced adaptive thermogenesis
This study is looking at how selenium, a nutrient found in some foods, affects your body's ability to generate heat when it's cold, which could help with weight management and overall health.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Hawaii at Manoa NIH-funded |
| Lab location | 1 site (Honolulu, United States) |
| Project ID | NIH-11061882 on NIH RePORTER |
What this research studies
This research investigates how selenium metabolism influences the body's ability to produce heat in response to cold exposure, a process known as adaptive thermogenesis. By studying brown adipose tissue, the research aims to understand the role of specific proteins that depend on selenium and how they contribute to energy balance and obesity prevention. The approach involves examining the biochemical pathways and signals that regulate these proteins, particularly in the context of cold-induced responses. Patients may benefit from insights into how dietary selenium could impact weight management and metabolic health.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals interested in weight management or those who may be affected by obesity-related conditions.
Not a fit: Patients who do not have concerns related to weight management or metabolic disorders may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for preventing obesity and improving metabolic health through dietary selenium.
How similar studies have performed: Previous research has shown promising results in understanding the role of selenium in metabolic processes, suggesting that this approach could yield valuable insights.
Where this research is happening
Honolulu, United States
- University of Hawaii at Manoa — Honolulu, United States (Active)
Researchers
- Principal investigator: Seale, Lucia Andreia — University of Hawaii at Manoa
- Study coordinator: Seale, Lucia Andreia
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.