How SARS-CoV-2 infection affects immune responses in children with and without asthma
Official title: Impact of SARS-CoV-2 infection on respiratory viral immune responses in children with and without asthma
Funded at Weill Medical Coll of Cornell Univ · NIH-10876498 · Data updated 2026-11-12
This study is looking at how COVID-19 affects the immune systems of children with asthma, especially how their genes might play a role in how they respond to the virus and vaccines, to help find better ways to keep them healthy.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Weill Medical Coll of Cornell Univ NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project start | July 1, 2023 |
| Project end | June 30, 2028 |
| Funding year | 2024 |
| Award (this year) | $799,479 |
| NIH project number | 5R01AI173504-02 |
| Project ID | NIH-10876498 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for participation are children aged 0-11 years, especially those diagnosed with asthma.
✕Less likely to help
Patients over the age of 11 or those without asthma may not receive direct benefits from this research.
What this research studies
This research investigates the impact of SARS-CoV-2 infection on the immune responses of children, particularly focusing on those with asthma. It aims to understand how genetic factors influence the severity of respiratory outcomes and immune responses to both the virus and vaccines. By studying a cohort of pediatric asthma patients in New York, the research will explore the relationship between common genetic variations and the immune system's reaction to respiratory infections. The findings could provide insights into how to better protect children, especially those with asthma, from respiratory illnesses.
Why it matters
Potential benefit: If successful, this research could lead to improved strategies for managing respiratory infections and vaccinations in children, particularly those with asthma.
How similar studies have gone: Previous research has shown that understanding genetic factors in respiratory infections can lead to significant advancements in treatment, suggesting this approach has potential for success.
Where this research is happening
-
Weill Medical Coll of Cornell Univ
New York, United States Active
Researchers
- Principal investigator: Worgall, Stefan — Weill Medical Coll of Cornell Univ
- Study coordinator: Worgall, Stefan
Related research
Other NIH-funded projects on the same topics.
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Impact of SARS-CoV-2 on kids with and without asthma
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.