NIH-funded research R01 grant

How salty drinking water affects hydration, kidney health, and blood pressure in hot environments

Official title: Drinking water salinity in a hot-dry environment: Hydration, kidney function, and blood pressure

Funded at Pennsylvania State University, the · NIH-10865975 · Data updated 2026-11-12

This study is looking at how drinking salty water affects your hydration, kidney health, and blood pressure, especially when it's hot and dry, to help create better guidelines for safe drinking water.

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Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionPennsylvania State University, the
NIH-funded
Lab location1 site (University Park, United States)
Project startSeptember 20, 2024
Project endJune 30, 2029
Funding year2024
Award (this year)$707,288
NIH project number1R01ES035402-01A1
Project IDNIH-10865975 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research include adults living in areas with high groundwater salinity, particularly those experiencing hot and dry climates.

Less likely to help

Patients who do not live in regions with salinity issues or who do not have concerns related to kidney function or blood pressure may not benefit from this research.

What this research studies

This research investigates the impact of increasing salinity in drinking water on hydration, kidney function, and blood pressure, particularly in hot and dry environments. It aims to understand how high salt levels in water can affect the body's ability to maintain water balance and how this may lead to kidney issues and hypertension. The study will involve collecting data on water salinity and its effects on health outcomes, focusing on both physiological responses and potential health risks. By establishing clear relationships between water salinity and health, the research seeks to inform guidelines for safe drinking water standards.

Why it matters

Potential benefit: If successful, this research could lead to improved health guidelines for drinking water salinity, potentially reducing the risk of kidney disease and hypertension in affected populations.

How similar studies have gone: While there has been some research on the effects of drinking water quality on health, this study's specific focus on salinity in relation to hydration and kidney function is relatively novel.

Where this research is happening

  • Pennsylvania State University, the
    University Park, United States
    Active

Researchers

  • Principal investigator: Rosinger, Asher Y. — Pennsylvania State University, the
  • Study coordinator: Rosinger, Asher Y.

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.