How saliva proteins affect taste and eating habits

Salivary Protein Influence on Taste and Feeding

['FUNDING_R01'] · STATE UNIVERSITY OF NEW YORK AT BUFFALO · NIH-10541143

This study looks at how proteins in saliva affect how we taste bitterness, especially in kids, to help make bitter foods and medicines more enjoyable and encourage healthier eating habits.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorSTATE UNIVERSITY OF NEW YORK AT BUFFALO (nih funded)
Locations1 site (AMHERST, UNITED STATES)
Trial IDNIH-10541143 on ClinicalTrials.gov

What this research studies

This research investigates how proteins in saliva influence the perception of bitter tastes, which can affect dietary choices. By examining how these proteins change in response to bitter foods, the study aims to understand their role in making bitter-tasting foods more acceptable, especially for children. The research involves testing taste reactions and measuring cellular responses to taste stimuli in a controlled environment. The findings could help improve the acceptance of pediatric medicines and promote healthier eating habits.

Who could benefit from this research

Good fit: Ideal candidates for this research include children and adults who may have difficulty accepting bitter-tasting foods or medications.

Not a fit: Patients who do not consume bitter foods or have no issues with taste perception may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to better strategies for making bitter medicines more palatable for children and encourage healthier eating patterns in both children and adults.

How similar studies have performed: Previous research has shown that understanding taste perception can lead to improved dietary choices, suggesting that this approach may yield valuable insights.

Where this research is happening

AMHERST, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.