How RNA messages find their way inside cells
Understanding the regulatory language of RNA localization
This project aims to understand how genetic messages (RNA) are directed to specific places within our cells, which is important for healthy cell function.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Colorado Denver NIH-funded |
| Lab location | 1 site (Aurora, UNITED STATES) |
| Project ID | NIH-11135341 on NIH RePORTER |
What this research studies
Our cells have many specialized areas, and for them to work correctly, genetic messages called RNA need to go to the right spot. When these messages get lost or go to the wrong place, it can lead to health problems, including developmental issues or neurological diseases. This research seeks to uncover the "language" that guides these RNA messages, identifying the specific signals within the RNA and the proteins that help them travel. By learning this language, we hope to create models that predict how RNA moves within cells.
Who could benefit from this research
Good fit: This foundational research does not directly involve patients but could eventually inform future treatments for those with neurological or developmental conditions linked to RNA localization issues.
Not a fit: Patients seeking immediate treatment options would not directly benefit from this basic science investigation.
Why it matters
Potential benefit: If successful, this work could provide foundational knowledge to understand and potentially address diseases caused by misdirected RNA messages in human cells.
How similar studies have performed: While the general concept of gene regulation is well-studied, understanding the specific "language" of RNA localization in this predictive way is a relatively novel and less explored area.
Where this research is happening
Aurora, UNITED STATES
- University of Colorado Denver — Aurora, United States (Active)
Researchers
- Principal investigator: Taliaferro, Jefferson Matthew — University of Colorado Denver
- Study coordinator: Taliaferro, Jefferson Matthew
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.