NIH-funded research R01 grant

How rewards and self-control shape kids' weight as they grow

Official title: Developmental trajectories of reinforcer pathology and childhood obesity

Funded at State University of New York at Buffalo · NIH-11298978 · Data updated 2026-11-12

Researchers will track how the pull of tasty food versus the appeal of activity, together with the ability to wait for rewards, relates to weight from early childhood through adolescence.

More Obesity research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionState University of New York at Buffalo
NIH-funded
Lab location1 site (Amherst, United States)
Project startMarch 15, 2025
Project endJanuary 31, 2030
Funding year2026
Award (this year)$589,877
NIH project number5R01DK139258-02
Project IDNIH-11298978 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates are children and teenagers from early childhood through adolescence, especially those at risk for or already showing excess weight.

Less likely to help

Adults well past adolescence or children with no interest in participating in behavioral testing or clinic visits are unlikely to benefit directly from participation.

What this research studies

This project follows children from early childhood into adolescence to see how the attraction to food versus physical activity and the ability to delay gratification change over time. Participants will complete questionnaires and behavioral tasks that measure how rewarding food and exercise feel and will do simple tests of impulse control. They may also have height/weight measured at clinic visits and wear activity monitors to track movement. Researchers will link those measures to changes in body mass to map pathways that lead to increased obesity risk as kids age.

Why it matters

Potential benefit: If successful, the work could point to better-timed prevention or personalized approaches that reduce obesity by targeting reward drives and self-control in kids.

How similar studies have gone: Prior research supports links between reward value, delay discounting, and obesity, but this longitudinal, developmental mapping across childhood into adolescence is relatively novel.

Where this research is happening

  • State University of New York at Buffalo
    Amherst, United States
    Active

Researchers

  • Principal investigator: Epstein, Leonard H — State University of New York at Buffalo
  • Study coordinator: Epstein, Leonard H

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.