How reproductive history affects heart and blood vessel health over time
Effect of reproductive history on longitudinal change in cardiac, vascular and lipid parameters
This study is looking at how a woman's pregnancy history and number of children can affect her heart health after menopause, and it's for women who want to understand how their past pregnancies might influence their risk of heart problems later in life.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Cincinnati Childrens Hosp Med Ctr NIH-funded |
| Lab location | 1 site (Cincinnati, United States) |
| Project ID | NIH-11001115 on NIH RePORTER |
What this research studies
This research investigates how a woman's reproductive history, including pregnancy and the number of live births, impacts long-term heart and blood vessel health, particularly after menopause. By examining existing data and conducting new assessments on women who participated in a previous health study, the research aims to identify changes in heart structure and cholesterol levels that may increase cardiovascular disease risk. Participants will undergo echocardiograms and provide information about their reproductive history to help clarify these relationships.
Who could benefit from this research
Good fit: Ideal candidates for this research are women who are pre- or peri-menopausal and have a history of pregnancy.
Not a fit: Patients who are not women or who have never been pregnant may not receive benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better understanding and prevention strategies for cardiovascular disease in women, particularly those who have been pregnant.
How similar studies have performed: Previous research has shown that pregnancy can significantly affect cardiovascular health, suggesting that this study's approach may yield valuable insights.
Where this research is happening
Cincinnati, United States
- Cincinnati Childrens Hosp Med Ctr — Cincinnati, United States (Active)
Researchers
- Principal investigator: Woo, Jessica G — Cincinnati Childrens Hosp Med Ctr
- Study coordinator: Woo, Jessica G
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.