How repeated flu vaccinations affect their effectiveness
Impact of repeated vaccination on the effectiveness of seasonal influenza vaccines
['FUNDING_R01'] · UNIVERSITY OF MISSOURI-COLUMBIA · NIH-11046523
This study is looking at how getting flu shots in consecutive years affects your immune system and how well the vaccine works, so we can better understand how repeated vaccinations help protect you from the flu.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF MISSOURI-COLUMBIA (nih funded) |
| Locations | 1 site (COLUMBIA, UNITED STATES) |
| Trial ID | NIH-11046523 on ClinicalTrials.gov |
What this research studies
This research investigates how receiving flu vaccinations in consecutive years impacts the body's immune response and the overall effectiveness of the vaccine. It aims to understand the patterns of antibody responses in individuals who have been vaccinated multiple times and how these responses may influence protection against the flu. By analyzing blood samples from participants, the study will measure the levels and types of antibodies produced after vaccination. The goal is to clarify the relationship between repeated vaccinations and their effectiveness, helping to inform future vaccination strategies.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals aged 6 months and older who have received flu vaccinations in previous seasons.
Not a fit: Patients who have never been vaccinated against influenza or those with specific contraindications to vaccination may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved flu vaccination strategies that enhance protection for individuals during flu seasons.
How similar studies have performed: Previous research has indicated that repeated vaccinations can influence immune responses, suggesting that this area of investigation is both relevant and necessary.
Where this research is happening
COLUMBIA, UNITED STATES
- UNIVERSITY OF MISSOURI-COLUMBIA — COLUMBIA, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: WAN, XIUFENG HENRY — UNIVERSITY OF MISSOURI-COLUMBIA
- Study coordinator: WAN, XIUFENG HENRY
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.