How reactive oxygen species influence nerve growth direction
NADPH oxidase regulates growth cone guidance
This study is looking at how certain molecules in our bodies help nerve cells grow and move, which is important for healing after injuries to the nervous system, and it's designed for anyone interested in understanding how we can improve recovery from such injuries.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Purdue University NIH-funded |
| Lab location | 1 site (West Lafayette, United States) |
| Project ID | NIH-10878785 on NIH RePORTER |
What this research studies
This research investigates the role of reactive oxygen species (ROS) in guiding the growth of nerve cells, which is crucial for proper nervous system development and repair. The study focuses on understanding how ROS, produced by a specific enzyme, affect the movement and growth of neuronal structures called growth cones. By exploring the cellular mechanisms and signaling pathways involved, the research aims to uncover how these molecules can influence nerve cell behavior and potentially improve recovery from nervous system injuries.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals under 21 years old who have experienced central nervous system injuries or related conditions.
Not a fit: Patients with conditions unrelated to nerve growth or central nervous system injuries may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for enhancing nerve regeneration and recovery after injuries.
How similar studies have performed: Previous research has shown that signaling molecules like ROS can play significant roles in cellular processes, suggesting potential for success in this area.
Where this research is happening
West Lafayette, United States
- Purdue University — West Lafayette, United States (Active)
Researchers
- Principal investigator: Suter, Daniel Marcel — Purdue University
- Study coordinator: Suter, Daniel Marcel
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.