How radiation affects the spread of prostate cancer
Radiation modulation of cell plasticity programs determine prostate cancer oligometastatic potential
This study is looking at how a special type of radiation therapy can help stop prostate cancer cells from spreading and becoming more aggressive, with the hope of improving treatment outcomes for patients.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Maryland Baltimore NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project ID | NIH-10910079 on NIH RePORTER |
What this research studies
This research investigates how radiation treatment can influence the behavior of prostate cancer cells, particularly their ability to spread to other parts of the body. It focuses on understanding the mechanisms behind metastasis, including how cancer cells may return to the primary tumor site and become more aggressive. By using a specific type of radiation therapy called stereotactic ablative radiation (SABR), the study aims to determine if targeting metastases can improve patient outcomes and prevent further spread of the disease.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients diagnosed with prostate cancer who have evidence of metastasis.
Not a fit: Patients with localized prostate cancer that has not spread beyond the primary site may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatment strategies that reduce the spread of prostate cancer and enhance survival rates.
How similar studies have performed: Previous research has shown promising results in using radiation to manage metastasis in various cancers, suggesting potential for success in this approach for prostate cancer.
Where this research is happening
Baltimore, United States
- University of Maryland Baltimore — Baltimore, United States (Active)
Researchers
- Principal investigator: Tran, Phuoc T. — University of Maryland Baltimore
- Study coordinator: Tran, Phuoc T.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.