How radiation affects metabolism in prostate cancer with limited spread.
Metabolic implications of radiation response in oligometastatic prostate cancer.
This study is looking at how radiation therapy works with the metabolism of prostate cancer cells that have spread a little, and it aims to find out if changing your diet can help improve treatment results for patients with this type of cancer.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Maryland Baltimore NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project ID | NIH-10910081 on NIH RePORTER |
What this research studies
This research investigates how radiation therapy interacts with the metabolism of prostate cancer cells that have spread to a limited extent, known as oligometastatic prostate cancer. By examining the metabolic changes in both the tumor and the patient, the study aims to identify which patients might benefit from dietary modifications to enhance treatment outcomes. The approach includes analyzing how specific genetic factors influence tumor metabolism and how these can be targeted to improve the effectiveness of radiation therapy. The goal is to optimize treatment strategies by potentially combining radiation with dietary interventions to boost the immune response against the cancer.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients diagnosed with oligometastatic prostate cancer who are undergoing or considering radiation therapy.
Not a fit: Patients with advanced metastatic prostate cancer or those not receiving radiation therapy may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatment strategies that enhance the effectiveness of radiation therapy for patients with oligometastatic prostate cancer.
How similar studies have performed: Preliminary data suggests that dietary modifications can positively influence tumor metabolism and enhance the effectiveness of radiation therapy, indicating a promising avenue for further exploration.
Where this research is happening
Baltimore, United States
- University of Maryland Baltimore — Baltimore, United States (Active)
Researchers
- Principal investigator: Simone, Nicole L — University of Maryland Baltimore
- Study coordinator: Simone, Nicole L
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.