How puberty hormones affect headaches in transmasculine teens
Official title: Effect of pubertal hormones on Headache in Transmasculine Adolescents
Funded at University of Colorado Denver · NIH-11023071 · Data updated 2026-11-12
This study is looking at how taking testosterone affects headaches in transmasculine teens, hoping to find ways to help manage their headaches better.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Colorado Denver NIH-funded |
| Lab location | 1 site (Aurora, UNITED STATES) |
| Project start | February 15, 2024 |
| Project end | January 31, 2029 |
| Funding year | 2025 |
| Award (this year) | $224,924 |
| NIH project number | 5K23NS130143-02 |
| Project ID | NIH-11023071 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are transmasculine adolescents aged 12 to 20 who are undergoing or considering gender-affirming hormone therapy.
✕Less likely to help
Patients who are not transmasculine or those outside the age range of 12 to 20 may not benefit from this research.
What this research studies
This research investigates the impact of gender-affirming hormone therapy with testosterone on headaches in transmasculine adolescents. By analyzing health records and conducting assessments, the study aims to understand how these hormones influence headache frequency and severity. Additionally, it will explore changes in brain structure and function related to hormone therapy. The goal is to provide insights that could lead to better headache management for this population.
Why it matters
Potential benefit: If successful, this research could lead to improved treatment strategies for headaches in transmasculine adolescents.
How similar studies have gone: While the specific focus on transmasculine adolescents is novel, previous research has shown that hormonal changes can significantly affect headache patterns in adolescents.
Where this research is happening
-
University of Colorado Denver
Aurora, United States Active
Researchers
- Principal investigator: Hranilovich, Jennifer — University of Colorado Denver
- Study coordinator: Hranilovich, Jennifer
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.