How puberty and rejection sensitivity affect preteen girls' mental health on social media

Rejection Sensitivity and Puberty in Mental Health Vulnerability to Social Media Experiences in Early Adolescent Girls

NIH-funded research Washington University · NIH-11182604

This project follows 250 girls ages 10–11 over three years to see how puberty, hormones, and sensitivity to rejection relate to their social media experiences and mental health.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionWashington University NIH-funded
Lab location1 site (Saint Louis, United States)
Project IDNIH-11182604 on NIH RePORTER

What this research studies

If you join, you'll be asked to complete brief phone-based surveys many times a day for two-week periods, once each year, to report on real-time social media interactions and feelings. The study also collects annual questionnaires about mood, measures of rejection sensitivity, and saliva samples to track hormone changes across puberty. Researchers will follow the same girls from about ages 10–13 to understand how early puberty and being sensitive to rejection may make social media experiences more harmful or less harmful. The goal is to map when and for whom online interactions are linked to increases or decreases in depression and suicidal thoughts.

Who could benefit from this research

Good fit: Girls who are about 10–11 years old at the start, willing to complete smartphone surveys and provide saliva samples, typically with parental consent, are ideal candidates.

Not a fit: Boys, older teens or adults, and children who do not use social media or cannot complete repeated phone-based reporting are unlikely to benefit directly from this project.

Why it matters

Potential benefit: This work could help parents, clinicians, and schools identify which girls are most at risk and when to offer support to prevent worsening depression and suicidal thoughts.

How similar studies have performed: Previous research links social media to worse mood in teens, but combining intense real-time reporting (microEMA) with hormone measures across early puberty is novel.

Where this research is happening

Saint Louis, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.