How proteins in mosquitoes affect malaria transmission
Official title: Plasmodium and Anopheles midgut interactive proteins influence malaria transmission
Funded at Florida International University · NIH-11048486 · Data updated 2026-11-12
This study is looking at how malaria-causing parasites interact with mosquitoes to help find new ways to stop the spread of malaria.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Florida International University NIH-funded |
| Lab location | 1 site (Miami, United States) |
| Project start | November 20, 2024 |
| Project end | October 31, 2029 |
| Funding year | 2025 |
| Award (this year) | $699,814 |
| NIH project number | 1R01AI179943-01A1 |
| Project ID | NIH-11048486 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals living in malaria-endemic regions who are at risk of malaria infection.
✕Less likely to help
Patients who do not reside in malaria-endemic areas or those who are not at risk of malaria infection may not benefit from this research.
What this research studies
This research investigates the interactions between Plasmodium parasites and the midgut of Anopheles mosquitoes, which are crucial for malaria transmission. By studying the molecular mechanisms involved in how these parasites invade the mosquito's midgut, the research aims to identify key proteins that facilitate this process. The approach includes large-scale screening of protein libraries to discover potential targets for disrupting these interactions, which could lead to new strategies for preventing malaria transmission.
Why it matters
Potential benefit: If successful, this research could lead to innovative methods for blocking malaria transmission, potentially saving millions of lives.
How similar studies have gone: Other research has shown promise in targeting mosquito vectors to disrupt malaria transmission, indicating that this approach has potential for success.
Where this research is happening
-
Florida International University
Miami, United States Active
Researchers
- Principal investigator: Li, Jun — Florida International University
- Study coordinator: Li, Jun
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.