How protein networks help shape cell membranes
Protein Networks as Synergistic Drivers of Membrane Remodeling
This study is looking at how certain proteins help shape cell membranes, which is important for how our cells work, and it could lead to new insights that help people with conditions like cancer and diabetes.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Texas at Austin NIH-funded |
| Lab location | 1 site (Austin, United States) |
| Project ID | NIH-11012854 on NIH RePORTER |
What this research studies
This research investigates the role of protein networks in the remodeling of cell membranes, which is crucial for various cellular processes. By focusing on how disordered protein domains contribute to membrane curvature, the research aims to uncover fundamental mechanisms that could impact diseases like cancer and diabetes. The approach involves studying clathrin-mediated endocytosis to understand how these protein networks function at a molecular level. Patients may benefit from insights gained about membrane defects that contribute to their conditions.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals affected by conditions such as cancer or diabetes, where membrane remodeling plays a significant role.
Not a fit: Patients with conditions unrelated to membrane curvature or cellular processes may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new therapeutic strategies for diseases linked to membrane curvature defects.
How similar studies have performed: Previous research has shown promising results in understanding membrane dynamics, but this approach focusing on disordered protein networks is relatively novel.
Where this research is happening
Austin, United States
- University of Texas at Austin — Austin, United States (Active)
Researchers
- Principal investigator: Stachowiak, Jeanne Casstevens — University of Texas at Austin
- Study coordinator: Stachowiak, Jeanne Casstevens
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.