NIH-funded research R01 grant

How prior knowledge helps memory in aging and Alzheimer's disease

Official title: The role of prior knowledge and event segmentation in age- and Alzheimer's-related changes in event memory

Funded at Kansas State University · NIH-11377637 · Data updated 2026-11-12

A study looks at how what people already know might help them remember everyday events, and how this changes with aging and Alzheimer’s.”

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionKansas State University
NIH-funded
Lab location1 site (Manhattan, United States)
Project startSeptember 15, 2022
Project endMay 31, 2027
Funding year2026
Award (this year)$381,605
NIH project number5R01AG075012-05
Project IDNIH-11377637 on NIH RePORTER

Who could benefit from this research

Could help

Adults age 65 and older, including those in the early stages of Alzheimer’s disease.

Less likely to help

People without memory concerns or those not showing early Alzheimer’s changes may not benefit from this approach.

What this research studies

This project uses real-world, dynamic stimuli to study how older adults form memories of everyday activities and whether semantic knowledge helps create stable memories. Researchers will test memory for continuous experiences to see how early Alzheimer’s disease affects this process. The goal is to understand if leveraging everyday knowledge can support memory and daily decision making in older adults and those at risk for Alzheimer’s. Findings could inform strategies to improve daily living, like healthcare decisions and interactions with technology.

Why it matters

Potential benefit: If successful, results could lead to ways to support daily memory and decision making for people with aging-related memory changes and early Alzheimer's.

How similar studies have gone: Previous work suggests memory can be influenced by prior knowledge, but this project extends understanding to real-world, continuous experiences in aging and Alzheimer’s.

Where this research is happening

  • Kansas State University
    Manhattan, United States
    Active

Researchers

  • Principal investigator: Bailey, Heather — Kansas State University
  • Study coordinator: Bailey, Heather

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.