How prenatal stress affects inflammation in unborn babies

Prenatal stress exposures and fetal inflammation during mid-gestation

NIH-funded research Emory University · NIH-10833662

This study looks at how stress in pregnant moms can affect inflammation in both them and their babies, especially during the middle of pregnancy, to help understand how stress might impact the health of mothers and their little ones.

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionEmory University NIH-funded
Lab location1 site (Atlanta, United States)
Project IDNIH-10833662 on NIH RePORTER

What this research studies

This research investigates the impact of maternal psychosocial stress on inflammation in both mothers and their unborn children during mid-gestation. It aims to understand how factors like stressful life events and lack of social support can lead to increased inflammation, which may affect fetal health. By analyzing maternal samples, the study seeks to uncover the relationship between maternal stress, inflammation, and fetal development, particularly in communities that experience higher levels of stress. The findings could help improve health outcomes for both mothers and their babies.

Who could benefit from this research

Good fit: Ideal candidates for this research are pregnant individuals experiencing psychosocial stress, particularly those from communities of color or low socioeconomic backgrounds.

Not a fit: Patients who are not pregnant or those without significant psychosocial stress may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to better understanding and interventions to reduce the risks of preterm birth and improve fetal health.

How similar studies have performed: Previous studies have shown a correlation between maternal stress and inflammation, but this research aims to explore this relationship in a novel way during mid-gestation.

Where this research is happening

Atlanta, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.