How prenatal alcohol exposure affects hearing in mice
Cellular mechanisms of auditory processing deficits in a mouse model of Fetal Alcohol Spectrum Disorders
This study is looking at how drinking alcohol during pregnancy might affect hearing in baby mice, helping us understand the brain changes that can lead to hearing problems in kids with fetal alcohol spectrum disorders.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Nebraska Medical Center NIH-funded |
| Lab location | 1 site (Omaha, United States) |
| Project ID | NIH-11091611 on NIH RePORTER |
What this research studies
This research investigates the impact of alcohol exposure during pregnancy on auditory processing deficits in a mouse model. By examining the central auditory pathway, the study aims to identify specific deficits in brain structures and cells that are affected by prenatal alcohol exposure. The researchers will analyze the functionality of auditory processing and the role of certain types of neurons in the auditory system. This work seeks to uncover the cellular mechanisms that lead to hearing impairments associated with fetal alcohol spectrum disorders.
Who could benefit from this research
Good fit: Ideal candidates for this research are children under 11 years old who have been exposed to alcohol in utero and exhibit auditory processing challenges.
Not a fit: Patients who have not been exposed to alcohol during pregnancy or do not exhibit auditory processing deficits may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to a better understanding of auditory processing deficits in children affected by prenatal alcohol exposure, potentially informing future interventions.
How similar studies have performed: Previous research has shown that understanding the cellular mechanisms of auditory processing can lead to significant insights, suggesting that this approach may yield valuable findings.
Where this research is happening
Omaha, United States
- University of Nebraska Medical Center — Omaha, United States (Active)
Researchers
- Principal investigator: Ragunathan, Padmashri — University of Nebraska Medical Center
- Study coordinator: Ragunathan, Padmashri
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.