NIH-funded research R01 grant

How pregnant people use cannabis (smoking, vaping, edibles) and other substances

Official title: Modes of Cannabis Administration and Polysubstance Use among Women Before and During Pregnancy

Funded at Kaiser Foundation Research Institute · NIH-11115861 · Data updated 2026-11-12

This project looks at the ways pregnant people use different cannabis products and other drugs before and during pregnancy and how those patterns relate to quitting and health outcomes.

More Pregnancy research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionKaiser Foundation Research Institute
NIH-funded
Lab location1 site (Oakland, UNITED STATES)
Project startSeptember 30, 2023
Project endJuly 31, 2028
Funding year2025
Award (this year)$677,280
NIH project number5R01DA058201-03
Project IDNIH-11115861 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates are pregnant people receiving prenatal care within Kaiser Permanente Northern California between 2021 and 2026, especially those who report or screen positive for cannabis use.

Less likely to help

People who are not pregnant, not receiving care at Kaiser Permanente Northern California, or who have never used cannabis are unlikely to gain direct benefit from participating.

What this research studies

You would be part of a large study using routine prenatal screening information and medical records from over 300,000 pregnancies at Kaiser Permanente Northern California from 2021–2026. The team combines self-reported use, urine toxicology results, and electronic health record data with local cannabis retailer and policy information to see which products people use and how that relates to frequency of use, cannabis use disorder, other substance use, quitting, and health effects. The research uses both large-scale data analysis and mixed methods to capture patterns across different racial, ethnic, and policy contexts. Findings will help clarify risks tied to specific modes of cannabis use during pregnancy.

Why it matters

Potential benefit: If successful, this work could help clinicians give clearer, more specific guidance and support to pregnant patients about risks of different cannabis products and quitting options.

How similar studies have gone: Previous studies have linked prenatal cannabis use to adverse outcomes but few large, diverse studies have examined differences by mode of use, so this builds on limited existing evidence.

Where this research is happening

  • Kaiser Foundation Research Institute
    Oakland, United States
    Active

Researchers

  • Principal investigator: Young-Wolff, Kelly Corinne — Kaiser Foundation Research Institute
  • Study coordinator: Young-Wolff, Kelly Corinne

Related research

Other NIH-funded projects on the same topics.

  • How pregnant women use cannabis and other substances across pregnancy

    This project looks at how women use cannabis before and during pregnancy and how patterns vary by who they are and by local policies, using health records from Kaiser Permanente to understand potential health impacts.

    NIH research Kaiser Foundation Research Institute · Oakland, UNITED STATES · NIH-11386446

  • Trajectories of Cannabis Use in Pregnancy

    This study follows pregnant people to understand how cannabis use patterns change across pregnancy and how those patterns relate to birth outcomes and child development.

    NIH research University of Maryland Baltimore · Baltimore, United States · NIH-11383471

  • Parental alcohol and cannabis use before, during, and after pregnancy

    This project looks at how pregnant people and their partners use alcohol and cannabis before, during, and after pregnancy to learn about timing and patterns of co-use.

    NIH research University of California, San Diego · La Jolla, United States · NIH-11195047

  • How cannabis use changes during pregnancy

    This project will follow pregnant people who use cannabis to track how their use changes across pregnancy and identify factors linked to those patterns.

    NIH research University of Maryland Baltimore · Baltimore, United States · NIH-11136878

  • Investigating alcohol and cannabis use before and during pregnancy

    This study is looking at how moms and dads use alcohol and cannabis before and during pregnancy to see how it might affect the baby’s development, and it’s for anyone interested in understanding the risks of these substances during this important time.

    NIH research University of California, San Diego · La Jolla, United States · NIH-10951450

  • How women use cannabis before and during pregnancy

    This study looks at how women use cannabis before and during pregnancy, including different ways they consume it like vaping or eating edibles, to see how this varies with their backgrounds and local laws, and how it might affect their health and their baby's health.

    NIH research Kaiser Foundation Research Institute · Oakland, UNITED STATES · NIH-10932969

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.