NIH-funded research R01 grant

How pregnancy exposure to environmental chemicals affects women's health later in life

Official title: Pregnancy Exposures to Chemical Mixtures and Later Metabolic Health and Endocrine Function Among Women in the Puerto Rico PROTECT Cohort

Funded at University of Michigan at Ann Arbor · NIH-11084411 · Data updated 2026-11-12

This study is looking at how being exposed to certain chemicals while pregnant might affect women's health later on, especially regarding diabetes and other health issues, and it's for women in Puerto Rico who want to understand how their pregnancy experiences could impact their long-term well-being.

More Pregnancy research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Michigan at Ann Arbor
NIH-funded
Lab location1 site (Ann Arbor, United States)
Project startAugust 21, 2020
Project endMay 31, 2026
Funding year2025
Award (this year)$385,778
NIH project number5R01ES032203-05
Project IDNIH-11084411 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are women who were pregnant during the study period and have lived in Puerto Rico, particularly those with a history of adverse pregnancy outcomes.

Less likely to help

Patients who did not experience pregnancy or who have not been exposed to the environmental chemicals being studied may not benefit from this research.

What this research studies

This research investigates the impact of exposure to environmental chemicals during pregnancy on women's metabolic health and endocrine function later in life. By studying a cohort of women in Puerto Rico, the research aims to understand how these exposures relate to conditions such as adult-onset diabetes and other adverse health outcomes. The study utilizes a rich dataset that includes biomarkers, health records, and participant questionnaires to track health changes over time. Participants will be followed up through the ECHO study to gather comprehensive health information.

Why it matters

Potential benefit: If successful, this research could lead to improved understanding and prevention strategies for metabolic disorders in women who were exposed to harmful chemicals during pregnancy.

How similar studies have gone: Other research has shown success in linking environmental exposures during pregnancy to later health outcomes, indicating that this approach is both relevant and necessary.

Where this research is happening

  • University of Michigan at Ann Arbor
    Ann Arbor, United States
    Active

Researchers

  • Principal investigator: Meeker, John D. — University of Michigan at Ann Arbor
  • Study coordinator: Meeker, John D.

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.