How pregnancy complications affect women's brain health later in life
Vascular Contributions to Cognitive Impairment after Adverse Pregnancy Outcomes: the nuMoM2b-Heart Health Study
['FUNDING_R01'] · COLUMBIA UNIVERSITY HEALTH SCIENCES · NIH-10675067
This study is looking at how complications during pregnancy, like preeclampsia and preterm delivery, might affect women's brain health later on, and it’s for women who have experienced these issues to help understand their future risks for cognitive problems.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | COLUMBIA UNIVERSITY HEALTH SCIENCES (nih funded) |
| Locations | 1 site (NEW YORK, UNITED STATES) |
| Trial ID | NIH-10675067 on ClinicalTrials.gov |
What this research studies
This research investigates the relationship between adverse pregnancy outcomes, such as preeclampsia and preterm delivery, and cognitive impairment in women. By following a diverse group of women who experienced these complications, the study aims to understand how these events may contribute to future risks of vascular cognitive impairment and dementia. Participants will undergo neurocognitive assessments and brain imaging to gather data on their cognitive health and vascular conditions. The findings could help identify women at risk and inform future interventions.
Who could benefit from this research
Good fit: Ideal candidates for this research are women who have had adverse pregnancy outcomes and are part of the nuMoM2b-HHS cohort.
Not a fit: Patients who have not experienced any adverse pregnancy outcomes may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better understanding and prevention strategies for cognitive decline in women who have experienced adverse pregnancy outcomes.
How similar studies have performed: Previous studies have shown that vascular contributions to cognitive impairment are significant, suggesting that this research could build on established findings in the field.
Where this research is happening
NEW YORK, UNITED STATES
- COLUMBIA UNIVERSITY HEALTH SCIENCES — NEW YORK, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: MILLER, ELIZA C — COLUMBIA UNIVERSITY HEALTH SCIENCES
- Study coordinator: MILLER, ELIZA C
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.