How poxviruses manipulate cell division and immune responses
Subversion of Cellular Mitotic and Antiviral Signaling by Poxviral Kinases
This study is looking at how certain viruses, called poxviruses, mess with the way our cells divide and fight off infections, and it’s for anyone interested in understanding how these viruses can outsmart our immune system.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Nebraska Lincoln NIH-funded |
| Lab location | 1 site (Lincoln, United States) |
| Project ID | NIH-10978213 on NIH RePORTER |
What this research studies
This research investigates how poxviruses affect the cellular processes that control cell division and the body's antiviral responses. By studying specific proteins produced by these viruses, the researchers aim to understand how these proteins interfere with normal cellular signaling pathways. This could reveal new insights into viral infections and how they evade the immune system. The approach involves comparing viral proteins with similar proteins found in human cells to uncover their mechanisms of action.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with viral infections, particularly those caused by poxviruses or related pathogens.
Not a fit: Patients with non-viral infections or those not affected by poxviruses may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for treating viral infections and enhancing antiviral responses in patients.
How similar studies have performed: Other research has shown promise in understanding viral manipulation of cellular processes, suggesting that this approach could yield valuable insights.
Where this research is happening
Lincoln, United States
- University of Nebraska Lincoln — Lincoln, United States (Active)
Researchers
- Principal investigator: Wiebe, Matthew S — University of Nebraska Lincoln
- Study coordinator: Wiebe, Matthew S
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.