How platelets interact with tumor cells in glioblastoma patients
Bidirectional interaction of platelets and tumor cells in patients with glioblastoma
This study is looking at how platelets in your blood interact with glioblastoma, a tough type of brain cancer, to find new ways to track how the cancer is doing and how well treatments are working, all without needing to do any painful biopsies.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | New York University School of Medicine NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-10684771 on NIH RePORTER |
What this research studies
This research investigates the interaction between platelets and tumor cells in patients with glioblastoma, a highly aggressive brain cancer. The study aims to develop new methods for monitoring tumor progression and treatment response without the need for invasive tissue biopsies. By analyzing blood samples, the researchers hope to identify tumor-educated platelets that carry specific genetic signatures related to the tumor, which could provide real-time insights into the patient's condition. This approach could lead to more effective monitoring strategies for glioblastoma patients.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults diagnosed with glioblastoma who are undergoing treatment.
Not a fit: Patients with other types of brain tumors or those who are not diagnosed with glioblastoma may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could enable non-invasive monitoring of glioblastoma progression and treatment response, improving patient management.
How similar studies have performed: While the concept of using blood-based biomarkers is being explored in other cancers, the specific approach of utilizing tumor-educated platelets in glioblastoma is relatively novel and has not been extensively tested.
Where this research is happening
New York, United States
- New York University School of Medicine — New York, United States (Active)
Researchers
- Principal investigator: Sulman, Erik — New York University School of Medicine
- Study coordinator: Sulman, Erik
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.