How plant-based diets affect heart health
Proteomic and epigenetic alterations associated with plant-based diets and CVD
['FUNDING_CAREER'] · UNIVERSITY OF WASHINGTON · NIH-11258205
This study is looking at how eating plant-based foods might affect heart health by exploring the proteins and genetic changes linked to different plant-based diets, and it's designed for people interested in understanding how their food choices can impact their risk of heart disease.
Quick facts
| Phase | ['FUNDING_CAREER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF WASHINGTON (nih funded) |
| Locations | 1 site (SEATTLE, UNITED STATES) |
| Trial ID | NIH-11258205 on ClinicalTrials.gov |
What this research studies
This research investigates the relationship between plant-based diets and cardiovascular disease (CVD) by examining the underlying biological mechanisms. It aims to identify specific proteins and epigenetic changes associated with different types of plant-based diets using advanced techniques like proteomics and DNA methylation analysis. The study will utilize data from well-established cohorts, including the Atherosclerosis Risk in Communities study, to explore how these dietary patterns influence heart health over time.
Who could benefit from this research
Good fit: Ideal candidates for this research are middle-aged individuals, particularly African American and European American participants, who are interested in the effects of their diet on heart health.
Not a fit: Patients who do not follow a plant-based diet or have existing severe cardiovascular conditions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better dietary recommendations that significantly reduce the risk of cardiovascular disease.
How similar studies have performed: Previous research has shown promising results in understanding the health benefits of plant-based diets, but this specific approach using proteomics and epigenetics is relatively novel.
Where this research is happening
SEATTLE, UNITED STATES
- UNIVERSITY OF WASHINGTON — SEATTLE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: KIM, HYUNJU — UNIVERSITY OF WASHINGTON
- Study coordinator: KIM, HYUNJU
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.