How plant-based diets affect heart disease risk
Official title: Proteomic and epigenetic alterations associated with plant-based diets and CVD
Funded at University of Washington · NIH-11052490 · Data updated 2026-11-12
This study is looking at how eating plant-based foods might affect heart health by exploring the proteins and genetic changes linked to different plant-based diets, and it's designed for anyone interested in how their diet could impact their risk of heart disease.
Quick facts
| Grant type | Career grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Washington NIH-funded |
| Lab location | 1 site (Seattle, United States) |
| Project start | September 2, 2023 |
| Project end | March 31, 2028 |
| Funding year | 2025 |
| Award (this year) | $149,713 |
| NIH project number | 5K01HL168232-04 |
| Project ID | NIH-11052490 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are middle-aged individuals, particularly African American and European American participants, who are interested in the effects of their diet on heart health.
✕Less likely to help
Patients who do not follow or are not interested in plant-based diets may not benefit from this research.
What this research studies
This research investigates the relationship between plant-based diets and cardiovascular disease (CVD) by examining the underlying biological mechanisms. It aims to identify specific proteins and DNA methylation patterns associated with different types of plant-based diets. The study will utilize data from the Atherosclerosis Risk in Communities (ARIC) study, which includes diverse participants, to analyze dietary intake and health outcomes. By understanding these mechanisms, the research seeks to clarify how plant-based diets can influence heart health.
Why it matters
Potential benefit: If successful, this research could lead to better dietary recommendations that significantly reduce the risk of cardiovascular disease.
How similar studies have gone: Previous research has shown promising results in understanding the health benefits of plant-based diets, suggesting that this approach could yield valuable insights.
Where this research is happening
-
University of Washington
Seattle, United States Active
Researchers
- Principal investigator: Kim, Hyunju — University of Washington
- Study coordinator: Kim, Hyunju
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.