How plant-based diets affect heart disease risk

Proteomic and epigenetic alterations associated with plant-based diets and CVD

NIH-funded research University of Washington · NIH-11052490

This study is looking at how eating plant-based foods might affect heart health by exploring the proteins and genetic changes linked to different plant-based diets, and it's designed for anyone interested in how their diet could impact their risk of heart disease.

Quick facts

Grant typeCareer grant
Study typeNIH-funded research
Funding institutionUniversity of Washington NIH-funded
Lab location1 site (Seattle, United States)
Project IDNIH-11052490 on NIH RePORTER

What this research studies

This research investigates the relationship between plant-based diets and cardiovascular disease (CVD) by examining the underlying biological mechanisms. It aims to identify specific proteins and DNA methylation patterns associated with different types of plant-based diets. The study will utilize data from the Atherosclerosis Risk in Communities (ARIC) study, which includes diverse participants, to analyze dietary intake and health outcomes. By understanding these mechanisms, the research seeks to clarify how plant-based diets can influence heart health.

Who could benefit from this research

Good fit: Ideal candidates for this research are middle-aged individuals, particularly African American and European American participants, who are interested in the effects of their diet on heart health.

Not a fit: Patients who do not follow or are not interested in plant-based diets may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to better dietary recommendations that significantly reduce the risk of cardiovascular disease.

How similar studies have performed: Previous research has shown promising results in understanding the health benefits of plant-based diets, suggesting that this approach could yield valuable insights.

Where this research is happening

Seattle, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.