How planarian stem cells respond to injury
Mechanisms driving stem cell responses to injury in planarians
['FUNDING_R01'] · CORNELL UNIVERSITY · NIH-10915673
This study looks at how special cells in planarians, a kind of flatworm, help them heal and regrow body parts after getting hurt, which could teach us more about how to improve healing in people too.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | CORNELL UNIVERSITY (nih funded) |
| Locations | 1 site (ITHACA, UNITED STATES) |
| Trial ID | NIH-10915673 on ClinicalTrials.gov |
What this research studies
This research investigates how stem cells in planarians, a type of flatworm, react to injury and contribute to tissue regeneration. By studying these unique organisms, which possess abundant stem cells capable of differentiating into various tissue types, the research aims to uncover the mechanisms that trigger stem cell proliferation and differentiation following injury. The approach includes monitoring and profiling these stem cells at a molecular level to understand their regenerative capabilities better. This could provide insights into enhancing regenerative processes in other organisms, including humans.
Who could benefit from this research
Good fit: Ideal candidates for benefiting from this research include individuals with injuries or conditions that impair tissue regeneration.
Not a fit: Patients with conditions unrelated to tissue regeneration or those who do not have injuries may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to breakthroughs in regenerative medicine, potentially improving healing processes in patients with injuries or tissue damage.
How similar studies have performed: Other research has shown promising results in understanding stem cell mechanisms in various organisms, but the specific approach using planarians is relatively novel.
Where this research is happening
ITHACA, UNITED STATES
- CORNELL UNIVERSITY — ITHACA, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: ADLER, CAROLYN ELIZABETH — CORNELL UNIVERSITY
- Study coordinator: ADLER, CAROLYN ELIZABETH
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.