How placental issues and the maternal-fetal environment affect brain development in children with congenital heart disease.
Influence of placental impairments and maternal-fetal environment on neurodevelopmental outcomes in Congenital Heart Disease
This study is looking at how issues with the placenta and the environment during pregnancy might affect the brain development of children with congenital heart disease, using safe MRI scans to help understand these connections and improve care for families.
Quick facts
| Grant type | Career grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Children's Hospital of Los Angeles NIH-funded |
| Lab location | 1 site (Los Angeles, United States) |
| Project ID | NIH-10867502 on NIH RePORTER |
What this research studies
This research investigates the impact of placental abnormalities and the maternal-fetal environment on the neurodevelopmental outcomes of children with congenital heart disease (CHD). By utilizing non-invasive magnetic resonance imaging (MRI), the study aims to identify how these factors contribute to neurodevelopmental delays in infants and children. The research focuses on understanding the relationship between cardiac physiology, placental health, and maternal-fetal risks to better predict outcomes for CHD patients. The findings could lead to improved diagnostic methods and interventions for affected families.
Who could benefit from this research
Good fit: Ideal candidates for this research are pregnant women carrying fetuses diagnosed with congenital heart disease.
Not a fit: Patients without congenital heart disease or those who are not pregnant may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better understanding and management of neurodevelopmental issues in children with congenital heart disease.
How similar studies have performed: Previous research has shown promising results in using MRI to study fetal development, indicating that this approach may yield valuable insights.
Where this research is happening
Los Angeles, United States
- Children's Hospital of Los Angeles — Los Angeles, United States (Active)
Researchers
- Principal investigator: Rajagopalan, Vidya — Children's Hospital of Los Angeles
- Study coordinator: Rajagopalan, Vidya
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.