How PFAS precursor chemicals increase exposure near contaminated sites

Assessing the Contribution of Polyfluoroalkyl Precursors to Diverse PFAS Exposures near Contaminated Sites

['FUNDING_OTHER'] · UNIVERSITY OF RHODE ISLAND · NIH-11123453

This project looks at how precursor chemicals lead to more PFAS pollution around contaminated Superfund sites and what that means for people living nearby.

Quick facts

Phase['FUNDING_OTHER']
Study typeNih_funding
SexAll
SponsorUNIVERSITY OF RHODE ISLAND (nih funded)
Locations1 site (KINGSTON, UNITED STATES)
Trial IDNIH-11123453 on ClinicalTrials.gov

What this research studies

If you live near a PFAS-contaminated site, this project studies where PFAS and their precursor chemicals are coming from and how they move through air, water, and fish. The team uses new environmental measurements and lab tests plus statistical and mechanistic tools to close gaps in what is being released and where it goes. Researchers link engineering measurements with biomedical work so exposure results can inform health studies and cleanup planning. The work focuses on precursors that break down into long-lasting PFAS and on atmospheric deposition as an important transport route.

Who could benefit from this research

Good fit: People who live, work, recreate, or fish near PFAS-contaminated Superfund or similar sites—including families with young children—are the most likely candidates to take part or benefit.

Not a fit: People who do not live near contaminated sites or have no concern about PFAS exposure may not see direct benefits from this project.

Why it matters

Potential benefit: If successful, this work could pinpoint major exposure sources and help guide cleanup or behavior changes to lower people's PFAS exposures.

How similar studies have performed: Prior studies have mostly targeted a few PFAS in drinking water, so this project expands to precursor chemicals and air pathways using new measurement and statistical methods.

Where this research is happening

KINGSTON, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.