How pet ownership affects gut health and Clostridioides difficile infections

Impact of pet contact on antimicrobial-associated dysbiosis and Clostridioides difficile infection

NIH-funded research University of Pennsylvania · NIH-11044056

This study is looking at how having pets might help your gut health bounce back after taking antibiotics, especially when it comes to fighting off infections like Clostridioides difficile, and we’d love for you to join us by sharing some samples and information to help us learn more!

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUniversity of Pennsylvania NIH-funded
Lab location1 site (Philadelphia, United States)
Project IDNIH-11044056 on NIH RePORTER

What this research studies

This research investigates the relationship between pet ownership and the gut microbiome's ability to resist Clostridioides difficile infections (CDI). It aims to understand how contact with pets may help restore gut health after antibiotic treatment, which often disrupts the natural microbiome. By analyzing the shared microbiota between pets and their owners, the study seeks to identify protective factors that could enhance recovery from CDI. Patients may be involved in providing samples and data to help uncover these connections.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals who have experienced Clostridioides difficile infections, particularly those who own pets.

Not a fit: Patients who do not have a history of Clostridioides difficile infections or do not own pets may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to new strategies for preventing and treating Clostridioides difficile infections by leveraging the benefits of pet ownership.

How similar studies have performed: Previous studies have suggested that pet ownership may provide protective effects against CDI, indicating that this research builds on promising findings.

Where this research is happening

Philadelphia, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.