How personality traits can predict the risk and progression of dementia

Personality Prediction of Dementia Risk and Progression

['FUNDING_OTHER'] · NORTHWESTERN UNIVERSITY AT CHICAGO · NIH-10980152

This study is looking at how your personality and the support you get from others might affect your brain health and the chances of developing Alzheimer's or related dementias, helping us find ways to keep your mind sharp for longer.

Quick facts

Phase['FUNDING_OTHER']
Study typeNih_funding
SexAll
SponsorNORTHWESTERN UNIVERSITY AT CHICAGO (nih funded)
Locations1 site (CHICAGO, UNITED STATES)
Trial IDNIH-10980152 on ClinicalTrials.gov

What this research studies

This research investigates the relationship between personality characteristics and the risk of developing Alzheimer's Disease and related dementias (ADRD). It aims to understand how personality traits and social support influence cognitive healthspan, which refers to the duration of cognitive function before and after a dementia diagnosis. The study will involve multiple investigations across four countries, examining how these factors may affect cognitive decline and resilience through various biological pathways. By identifying these associations, the research seeks to provide insights into potential interventions that could enhance cognitive health in individuals at risk for dementia.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals at risk for Alzheimer's Disease or related dementias, particularly those with identifiable personality traits that may influence cognitive health.

Not a fit: Patients who do not have any risk factors for dementia or those with advanced stages of dementia may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to new strategies for predicting and potentially delaying the onset of dementia based on personality traits.

How similar studies have performed: Previous research has shown promising results in understanding the links between personality traits and cognitive health, suggesting that this approach could yield valuable insights.

Where this research is happening

CHICAGO, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Conditions: Alzheimer's disease and related dementia, Alzheimer's disease and related disorders, Alzheimer's disease brain, Alzheimer's disease diagnosis, Alzheimer's disease or a related dementia

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.