How people with central vision loss aim and keep things in view

Oculomotor Demands for Target Stabilization without Central Vision

NIH-funded research Smith-Kettlewell Eye Research Institute · NIH-11309171

This project looks at how people with central vision loss from conditions like age-related macular degeneration move their eyes and head to find and keep things in view during everyday tasks.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionSmith-Kettlewell Eye Research Institute NIH-funded
Lab location1 site (San Francisco, United States)
Project IDNIH-11309171 on NIH RePORTER

What this research studies

You would take part in vision and eye-movement tests that recreate everyday situations, such as shifting gaze between objects at different distances, keeping images steady while moving, and coordinating eye and head movements. The team uses binocular eye-tracking and motion tasks to compare people with central field loss to people with normal vision. They will study how losing central vision and using eccentric fixation in one or both eyes affects the way you look around and stabilize images on the retina. The work focuses on behaviors that matter for safe walking, driving, and avoiding falls in busy environments.

Who could benefit from this research

Good fit: Ideal candidates are adults with central visual field loss, such as from age-related macular degeneration, who notice difficulty with depth perception, mobility, or using eccentric fixation.

Not a fit: People without central visual field loss or whose vision problems do not affect the central retina are unlikely to receive direct benefit from this project.

Why it matters

Potential benefit: If successful, this work could lead to better rehabilitation strategies or tools that help people with central vision loss navigate more safely and reduce falls and collisions.

How similar studies have performed: Prior studies have described static visual limits in macular degeneration, but applying binocular eye-tracking in naturalistic gaze-shifting and stabilization tasks is relatively new and not yet widely validated.

Where this research is happening

San Francisco, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.