How people across the U.S. get and carry naloxone

A National Survey on Naloxone Use and Access

NIH-funded research University of Pennsylvania · NIH-11502195

This project will learn how people in the United States find, buy, and carry naloxone, and how new over-the-counter options affect those choices.

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionUniversity of Pennsylvania NIH-funded
Lab location1 site (Philadelphia, United States)
Project IDNIH-11502195 on NIH RePORTER

What this research studies

You would be invited to complete online surveys each year about whether you carry naloxone, where you obtained it, and what makes it hard or easy to get. The team will use a nationally representative online sample plus a targeted sample to capture both broad patterns and groups more likely to carry naloxone. Survey questions include short scenarios and price options to see how cost and availability influence decisions, and the project will track reactions to newly approved over-the-counter naloxone products in near real time. Responses will be used to map barriers to access, common sources of naloxone, and changes over the three-year timeframe.

Who could benefit from this research

Good fit: U.S. adults are eligible, especially people who carry or might carry naloxone, friends or family of people who use opioids, and pharmacy customers interested in naloxone access.

Not a fit: People living outside the United States or those seeking immediate clinical treatment for opioid use disorder are unlikely to gain direct medical benefit from participating in the surveys.

Why it matters

Potential benefit: If successful, the findings could help make naloxone easier and more affordable to obtain, potentially increasing the number of people who carry it and helping prevent overdose deaths.

How similar studies have performed: While community naloxone distribution programs have reduced overdose deaths, there is limited national data on naloxone carrying and OTC purchasing, so this approach is relatively new and fills a known evidence gap.

Where this research is happening

Philadelphia, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.